Mohammad Kazem Emami Meybodi; Hamid Reza Rasouli; Mohammad Ghafouri; Shabnam Akhoundzadeh Bafghi; Mojtaba Ghafouri
Volume 20, Issue 6 , 2018, Pages 1-7
Abstract
Background: Osteoarthritis (OA) is a highly prevalent chronic degenerative joint disease with different risk factors, which need to be investigated in order to perform more appropriate interventions in earlier phases of Osteoarthritis.Objectives: Therefore, the aim of this study was to determine the ...
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Background: Osteoarthritis (OA) is a highly prevalent chronic degenerative joint disease with different risk factors, which need to be investigated in order to perform more appropriate interventions in earlier phases of Osteoarthritis.Objectives: Therefore, the aim of this study was to determine the correlation between hip morphology and hip Osteoarthritis. Methods: This cross-sectional study was conducted on patients aged 15 to 60 years old with hip problems, diagnosed with hip Os- teoarthritis, compared with healthy individuals as the control group. Then radiographic parameters, such as alpha angle, acetabular angle of sharp (AA), lateral center-edge angle (LCEA), femoral neck-shaft angle (FNA), coxa profunda, acetabular protrusio, crossover sign, posterior wall sign, and the ischial sign were measured by pelvic (AP) X-ray, using PACS systems in both groups. Results: This study found that alpha angle and AA were significantly greater in OA patients as compared to healthy individuals (P < 0.001). Furthermore, LCEA was significantly greater in the Osteoarthritis group on the left side as compared to the control group (38.93 ± 8.43 versus 36.81 ± 4.74, P = 0.042) yet LCEA on the right side and total amount were not different between the twogroups (P>0.05). By grouping studied angles, it was found that the frequency of alpha angle > 55°, AA > 38°, and LCEA > 40° were significantly higher in the OA group as compared to the control group (P < 0.05). Furthermore, the researchers observed that the fre- quency of acetabular protrusio (P = 0.013) and posterior wall sign were significantly higher in the OA group as compared to healthy individuals (P < 0.05). Conclusions: The current results showed that the higher Body Mass Index (BMI), greater alpha and acetabular angles, sharp, lateral center-edge angle center-edge angle, the higher rate of a posterior wall sign, and acetabular protrusio increased the risk of OA, which support that these structural changes are major contributors to OA development.
Seyed Mohammad Heshmati; Ali Ebrahimi; Hamid Reza Rasouli
Volume 19, Issue 3 , March 2017, , Pages 1-11
Abstract
Context: Fluid therapy is the basis of resuscitation; however, there has been a heated debate on the choice of appropriate fluid. This study mainly aimed to determine which fluid is correlated with a decline in mortality rate and can be the most suitable choice for each group of patients.Evidence Acquisition: ...
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Context: Fluid therapy is the basis of resuscitation; however, there has been a heated debate on the choice of appropriate fluid. This study mainly aimed to determine which fluid is correlated with a decline in mortality rate and can be the most suitable choice for each group of patients.Evidence Acquisition: We conducted a systematic search on Google Scholar, Web of Science, Scopus, BMJ Journals, Thieme, Path Consult, BIDS Index, Embase, Medline, and Cochrane Controlled Trials up to April 2016. The relevant studies were those that provided a comparison between the effects of different fluids on the mortality rate of patients. Two independent authors participated in the evaluating methodological quality, selecting eligible studies, and extracting the relevant data from the studies.Results: We selected 26 out of 2724 potential randomized controlled trials (RCTs) from the databases for both quantitative and qualitative analyses resulting in a total of 22882 patients receiving either colloid or crystalloid fluids. The approximated pooled Relative risk (RR) for the death of patients who had been resuscitated with crystalloid fluid therapy rather than colloid fluid therapy was 1.008. This meta-analysis illustrated that there was a decline in the mortality rate with borderline significance in both traumatic and hypovolemic patients through utilizing colloid fluids. The mortality reduced more by using dextran and albumin than using crystalloid fluids.Conclusions: The results of this meta-analysis show that colloid fluids can increase the successful resuscitation rate compared to crystalloid fluids especially in traumatic and hypovolemic patients.Some of the colloids like albumin and dextran have a positive effect on reducing the mortality rate but others like Hetastarch (HES) increase the mortality rate compared to normal saline (NS).
